Load data

## # A tibble: 8 × 10
##   K_Denovo Lambda Log_Like   BIC Log_Likes  BICs       Cosine Alpha  Beta  M_R  
##      <dbl>  <dbl>    <dbl> <dbl> <list>     <list>     <list> <list> <lis> <lis>
## 1        1    0     -1964. 4553. <dbl [4]>  <dbl [4]>  <dbl>  <df>   <df>  <df> 
## 2        1    0.1   -1965. 4553. <dbl [4]>  <dbl [4]>  <dbl>  <df>   <df>  <df> 
## 3        1    0.2   -1965. 4553. <dbl [4]>  <dbl [4]>  <dbl>  <df>   <df>  <df> 
## 4        1    0.3   -1965. 4554. <dbl [3]>  <dbl [3]>  <dbl>  <df>   <df>  <df> 
## 5        2    0     -1174. 3595. <dbl [9]>  <dbl [9]>  <dbl>  <df>   <df>  <df> 
## 6        2    0.1   -1174. 3595. <dbl [23]> <dbl [23]> <dbl>  <df>   <df>  <df> 
## 7        2    0.2   -1174. 3596. <dbl [20]> <dbl [20]> <dbl>  <df>   <df>  <df> 
## 8        2    0.3   -1174. 3596. <dbl [23]> <dbl [23]> <dbl>  <df>   <df>  <df>

Overall insights on :

k, \(\lambda\), log-likelihood, BIC & Constructed Phylogeny

Best Run info (log-likelihood)

## [1] "Best K_Denovo : 2"
## [1] "Best Lambda : 0"

Best Run info (BIC)

## [1] "Best K_Denovo : 2"
## [1] "Best Lambda : 0"

Visualize Alpha for Best BIC

Visualize Fixed Beta

Visualize Inferred vs. Expected SBS1 Signature

first plot represents expected signature and second plot represents inferred signature.

## [1] "cosine similarity between two signatures : 0.793133175485402"

Visualize Inferred vs. Expected Unknown Signature

first plot represents expected signature and second plot represents inferred signature.

## [1] "cosine similarity between two signatures : 0.983823950239068"